Background:

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Integrin alpha-X ;CD11 antigen-like family member C;Leu M5;Leukocyte adhesion glycoprotein p150,95 alpha chain;Leukocyte adhesion receptor p150,95;CD antigen CD11c; Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD antigen CD11c

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 920-980

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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