Background:

This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Integrin alpha-D; ITGAD; Integrin alpha-D; ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD11d

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human ITGAD. AA range:901-950

Concentration:

1 mg/ml

Molecular weight:

126886

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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