Background:

IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,Contains 1 IGFBP N-terminal domain.,Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,

Classification:

Primary antibody

Alternative names:

Insulin-like growth factor-binding protein-like 1 ;IGFBP-related protein 10;Insulin-like growth factor-binding-related protein 4;IGFBP-rP4

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from part region of human protein

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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