Background:

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Histone deacetylase 2; HDAC2; Histone deacetylase 2; HD2

Species reactivity:

Human, Mouse, Rat, Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human HDAC2 around the phosphorylation site of Ser394. AA range:360-409

Concentration:

1 mg/ml

Molecular weight:

55364

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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