Background:

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,Contains 1 AXH domain.,Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,

Classification:

Primary antibody

Alternative names:

HMG box-containing protein 1; HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human HBP1 around the phosphorylation site of Ser402. AA range:371-420

Concentration:

1 mg/ml

Molecular weight:

57645

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

More info:

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