Background:

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Classification:

Primary antibody

Alternative names:

Growth-regulated alpha protein; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha;1-73; Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GROalpha. AA range:39-88

Concentration:

1 mg/ml

Molecular weight:

11301

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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