Background:

Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).,Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.,

Classification:

Primary antibody

Alternative names:

N-formyl peptide receptor 2 ;FMLP-related receptor I;FMLP-R-I;Formyl peptide receptor-like 1;HM63;Lipoxin A4 receptor;LXA4 receptor;RFP

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 130-210

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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