Background:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Classification:

Primary antibody

Alternative names:

Peptidyl-prolyl cis-trans isomerase FKBP3 ;PPIase FKBP3;EC 5.2.1.8;25 kDa FK506-binding protein;25 kDa FKBP;FKBP-25;FK506-binding protein 3;FKBP-3;Immunophilin FKBP25;Rapamycin-selecti

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 140-220

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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