Background:

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Classification:

Primary antibody

Alternative names:

Protocadherin Fat 1 ;Cadherin family member 7;Cadherin-related tumor suppressor homolog;Protein fat homolog [Cleaved into: Protocadherin Fat 1, nuclear form]

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 1140-1220

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

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