Background:

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Classification:

Primary antibody

Alternative names:

Protein C-ets-1; ETS1; EWSR2; Protein C-ets-1; p54

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phospho-peptide around the phosphorylation site of human Ets-1 (phospho Ser251)

Concentration:

1 mg/ml

Molecular weight:

50202

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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