Background:

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Endothelin B receptor ;ET-B;ET-BR;Endothelin receptor non-selective type; Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic Peptide of Endothelin B Receptor

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

More info:

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