Background:

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Classification:

Primary antibody

Alternative names:

EGFR ;Phospho-Tyr998; Epidermal growth factor receptor; EC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human EGFR (Phospho-Tyr998)

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, WB

Storage:

-20°C for 1 year

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