Background:

The DHR-2 domain is necessary for the GEF activity.,Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR-1 (CZH-1) domain.,Contains 1 DHR-2 (CZH-2) domain.,Contains 1 PH domain.,subunit:Interacts with CDC42.,

Classification:

Primary antibody

Alternative names:

Dedicator of cytokinesis protein 11 ;Activated Cdc42-associated guanine nucleotide exchange factor;ACG;Zizimin-2

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from part region of human protein

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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