Background:

Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP-binding domain.,Contains 1 helicase C-terminal domain.,subunit:Interacts with DDX58 and probably blocks its homomultimerization.,

Classification:

Primary antibody

Alternative names:

Probable ATP-dependent RNA helicase DHX58 ;EC 3.6.4.13;Probable ATP-dependent helicase LGP2;Protein D11Lgp2 homolog;RIG-I-like receptor 3;RLR-3;RIG-I-like receptor LGP2;RLR

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 451-500

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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