Background:

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

Classification:

Primary antibody

Alternative names:

Cytochrome b-245 light chain ;Cytochrome b;558 alpha chain;Cytochrome b558 subunit alpha;Neutrophil cytochrome b 22 kDa polypeptide;Superoxide-generating NADPH oxidase light chain subunit;p22

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 80-160

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

More info:

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