Background:

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

Cyclic AMP-responsive element-binding protein 1; CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CREB around the phosphorylation site of Ser121. AA range:91-140

Concentration:

1 mg/ml

Molecular weight:

36688

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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