Background:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Classification:

Primary antibody

Alternative names:

Claudin-5; CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Claudin 5 around the phosphorylation site of Tyr217. AA range:169-218

Concentration:

1 mg/ml

Molecular weight:

23147

Applications:

IHC-p, IF, WB, ELISA

Storage:

-20°C for 1 year

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