Background:

The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Low affinity immunoglobulin gamma Fc region receptor II-b

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CD32. AA range:277-326

Concentration:

1 mg/ml

Molecular weight:

34044

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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