Background:

Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms.

Classification:

Primary antibody

Alternative names:

Calcium-binding protein 1 ;CaBP1;Calbrain;Caldendrin; Calcium-binding protein 1; CaBP1; Calbrain; Caldendrin

Species reactivity:

Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic Peptide of CABP

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, IHC-p, IF

Storage:

-20°C for 1 year

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