Background:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Classification:

Primary antibody

Alternative names:

Proto-oncogene c-Fos; FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FOS around the phosphorylation site of Thr232. AA range:201-250

Concentration:

1 mg/ml

Molecular weight:

40695

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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