Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia.

Classification:

Primary antibody

Alternative names:

Growth/differentiation factor 2 ;GDF-2;Bone morphogenetic protein 9;BMP-9; Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 371-420

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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