Background:

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Classification:

Primary antibody

Alternative names:

Angiogenin; ANG; RNASE5; Angiogenin; Ribonuclease 5; RNase 5

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the N-terminal region of human ANG. AA range:11-60

Concentration:

1 mg/ml

Molecular weight:

16550

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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