Background:

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation| but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione| a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde| a potent irritant and sensitizing agent that causes lacrymation| rhinitis| pharyngitis| and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Classification:

Primary antibody

Alternative names:

Alcohol dehydrogenase class-3 ;EC 1.1.1.1;Alcohol dehydrogenase 5;Alcohol dehydrogenase class chi chain;Alcohol dehydrogenase class-III;Glutathione-dependent formaldehyde dehydrogenase;FALDH

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 280-360

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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