Background:

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase| which may be involved in normal physiological processes such as cell migration| cell adhesion| cell-cell and cell-matrix interactions| and signal transduction. It is proposed to play a role in pathological processes| such as cancer| inflammatory diseases| renal diseases| and Alzheimer's disease.

Classification:

Primary antibody

Alternative names:

Disintegrin and metalloproteinase domain-containing protein 19 ;ADAM 19;EC 3.4.24.-;Meltrin-beta;Metalloprotease and disintegrin dendritic antigen marker;MADDAM

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 180-260

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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