Background:

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain| a disintegrin-like domain| as well as a EGF-like domain. Through its disintegrin-like domain| this protein specifically interacts with the integrin beta chain| beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner| suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Classification:

Primary antibody

Alternative names:

Disintegrin and metalloproteinase domain-containing protein 15 ;ADAM 15;EC 3.4.24.-;Metalloprotease RGD disintegrin protein;Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 15

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 50-130

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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