Background:

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain| proline rich region and Src-homology 3 (SH3) domain| and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

ABI gene family member 3 ;New molecule including SH3;Nesh

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from part region of human protein

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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