Background:

This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such| it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Classification:

Primary antibody

Alternative names:

Tyk 2 ;Phospho Tyr292; Non-receptor tyrosine-protein kinase TYK2; EC 2.7.10.2

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)

Concentration:

1 mg/ml

Molecular weight:

130570

Applications:

WB, ELISA

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

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