Background:

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants| vertebrates| and invertebrates| and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis| for instance| induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Classification:

Primary antibody

Alternative names:

TULP3

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human TULP3

Concentration:

1 mg/ml

Molecular weight:

48620

Applications:

WB

Storage:

-20°C for 1 year

More info:

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