Background:

This gene encodes a member of the tripartite motif (TRIM) family| whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains| a RING finger region| a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism| an autosomal recessive disorder that involves several tissues of mesodermal origin.

Classification:

Primary antibody

Alternative names:

TRI37; E3 ubiquitin-protein ligase TRIM37; EC 6.3.2.-; Mulibrey nanism protein; Tripartite motif-containing protein 37

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human TRI37

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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