Background:

This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor| known as somatoliberin| which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors| and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism| while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed.

Classification:

Primary antibody

Alternative names:

SLIB

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human SLIB

Concentration:

1 mg/ml

Molecular weight:

11880

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com