Background:

This gene encodes gamma-sarcoglycan| one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin| syntrophin| alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy| in particular limb-girdle muscular dystrophy| type 2C (LGMD2C).

Classification:

Primary antibody

Alternative names:

SGCG

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human SGCG

Concentration:

1 mg/ml

Molecular weight:

32010

Applications:

WB

Storage:

-20°C for 1 year

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