Background:

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose| insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

SESN3

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human SESN3

Concentration:

1 mg/ml

Molecular weight:

54120

Applications:

WB

Storage:

-20°C for 1 year

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