Background:

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex| which includes SIN3| SAP30| HDAC1| HDAC2| RbAp46| RbAp48| and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Classification:

Primary antibody

Alternative names:

SAP18

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human SAP18

Concentration:

1 mg/ml

Molecular weight:

16830

Applications:

WB

Storage:

-20°C for 1 year

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