Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells| and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release| stimulation of prolactin secretion| and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Classification:

Primary antibody

Alternative names:

S-100A6; Protein S100-A6; Calcyclin; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; PRA; S100 calcium-binding protein A6

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human S-100A6

Concentration:

1 mg/ml

Molecular weight:

9900

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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