Background:

This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape| attachment| and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

Classification:

Primary antibody

Alternative names:

RhoA ;Phospho Ser188; Transforming protein RhoA; Rho cDNA clone 12; h12

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human RhoA (Phospho Ser188)

Concentration:

1 mg/ml

Molecular weight:

21230

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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