Background:

It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.|PTM:Phosphorylated upon DNA damage| probably by ATM or ATR.|Belongs to the replication factor A protein 1 family.|subunit:Heterotrimer of 70| 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.|

Classification:

Primary antibody

Alternative names:

RFA1; Replication protein A 70 kDa DNA-binding subunit; RP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding protein

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human RFA1

Concentration:

1 mg/ml

Molecular weight:

67760

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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