Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation. This PTP possesses an extracellular region| a single transmembrane region| and a single intracytoplasmic catalytic domain| and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver| and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

PTPRH

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human PTPRH

Concentration:

1 mg/ml

Molecular weight:

122650

Applications:

WB

Storage:

-20°C for 1 year

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