Background:

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis.

Classification:

Primary antibody

Alternative names:

PROC ;light chain; Cleaved-Leu179; Vitamin K-dependent protein C; EC 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide;

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human PROC (light chain| Cleaved-Leu179)

Concentration:

1 mg/ml

Molecular weight:

50710

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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