Background:

This gene encodes transthyretin| one of the three prealbumins including alpha-1-antitrypsin| transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid| and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition| affecting predominantly peripheral nerve and/or the heart| and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy| euthyroid hyperthyroxinaemia| amyloidotic vitreous opacities| cardiomyopathy| oculoleptomeningeal amyloidosis| meningocerebrovascular amyloidosis| carpal tunnel syndrome| etc.

Classification:

Primary antibody

Alternative names:

Prealbumin; Transthyretin; ATTR; Prealbumin; TBPA

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human Prealbumin

Concentration:

1 mg/ml

Molecular weight:

16170

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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