Background:

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein| estrogen receptor| and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized| it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma| (2) act as a transcriptional activator of the heme-oxygenase-1 gene| and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

PRDM2

Species reactivity:

Human, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human PRDM2

Concentration:

1 mg/ml

Molecular weight:

188980

Applications:

WB

Storage:

-20°C for 1 year

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