Background:

The protein encoded by this gene contains a PDZ domain and a LIM domain| indicating that it may be involved in cytoskeletal assembly. In support of this| the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.

Classification:

Primary antibody

Alternative names:

PDLI3

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human PDLI3

Concentration:

1 mg/ml

Molecular weight:

40040

Applications:

WB

Storage:

-20°C for 1 year

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