Background:

This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE)| a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex| the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

Classification:

Primary antibody

Alternative names:

PDE6D

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human PDE6D

Concentration:

1 mg/ml

Molecular weight:

16500

Applications:

WB

Storage:

-20°C for 1 year

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