Background:

This gene is a member of the type IV| cyclic AMP (cAMP)-specific| cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

PDE4B

Species reactivity:

Human, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human PDE4B

Concentration:

1 mg/ml

Molecular weight:

80960

Applications:

WB

Storage:

-20°C for 1 year

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