Background:

The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization| the anchoring of otoconial membranes and cupulae to the neuroepithelia| and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness| type 18B. Alternative splicing of this gene results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

OTOG

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human OTOG

Concentration:

1 mg/ml

Molecular weight:

321750

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

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