Background:

This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor| alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

NuMA ;Thr2055; Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phosho peptide around human NuMA (Thr2055)

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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