Background:

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism| so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines| such as familial hypertriglyceridemia (FHTG).

Classification:

Primary antibody

Alternative names:

NTCP2

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human NTCP2

Concentration:

1 mg/ml

Molecular weight:

38280

Applications:

WB

Storage:

-20°C for 1 year

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