Background:

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition| a polymorphic repeat region is found in the C-terminus of the encoded protein.

Classification:

Primary antibody

Alternative names:

NCoA-3 ;Acetyl Lys616; Nuclear receptor coactivator 3; NCoA-3; EC 2.3.1.48; ACTR; Amplified in breast cancer 1 protein; AIB-1; CBP-interacting protein; pCIP; Class E basic helix-loop-helix protein 42; bHLHe42; Receptor-associated coactivator 3; RAC-3; Steroid receptor coactivator protein 3; SRC-3; Thyroid hormone receptor activator molecule 1; TRAM-1

Species reactivity:

Human, Rat, Mouse,

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human NCoA-3 (Acetyl Lys616)

Concentration:

1 mg/ml

Molecular weight:

156640

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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