Background:

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein| which contains an N-terminal pyrin domain| a NACHT domain| a NACHT-associated domain| and a C-terminus leucine-rich repeat region| functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

NAL12

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human NAL12

Concentration:

1 mg/ml

Molecular weight:

116710

Applications:

WB

Storage:

-20°C for 1 year

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