Background:

The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI)| the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and| thereby| CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

Classification:

Primary antibody

Alternative names:

NAGS

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human NAGS

Concentration:

1 mg/ml

Molecular weight:

58740

Applications:

WB

Storage:

-20°C for 1 year

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