Background:

This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions| including cytokinesis| cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17| Epstein syndrome| Alport syndrome with macrothrombocytopenia| Sebastian syndrome| Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Classification:

Primary antibody

Alternative names:

Myosin IIa ;Ser1943 ; Myosin-9; Cellular myosin heavy chain; type A; Myosin heavy chain 9; Myosin heavy chain; non-muscle IIa; Non-muscle myosin heavy chain A; NMMHC-A; Non-muscle myosin heavy chain IIa; NMMHC II-a; NMMHC-IIA

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phosho peptide around human Myosin IIa (Ser1943)

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com